.

Curriculum Vitae

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Dr. A. Jayakrishnan, Ph.D., F. A. Sc.,

Vice Chancellor,
University of Kerala,
Trivandrum 695 034, India.
Tel: +91-471+2306634 (O);
+91-471-2353309 (Res);
Fax: +91-471-2302898
Email: vicechancellor@vsnl.net, ajk@iitm.ac.in, dr_jayakrishnan@yahoo.co.in

 
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Personal:
Born April 25, 1953
Education:

Ph.D in Chemistry, Indian Institute of Technology, Madras, India, 1980.
 
M.Sc in Chemistry, University of Calicut, India, 1975, First Class, First Rank.
 
B.Sc in Chemistry, University of Calicut, India, 1973, First Class.

  Experience:

Vice Chancellor
University of Kerala
Trivandrum 695 034, Kerala, India.
December 2008-Present

Vice Chancellor-in charge
Cochin University of Science and Technology
Cochin 682 022, Kerala, India.
February 22, 2009 to 4th january 2010

Professor, Department of Biotechnology
Indian Institute of Technology, Madras, India.
April 2007-December 2008

Scientist and Head, Polymer Chemistry Division,
Sree Chitra Tirunal Institute, Trivandrum, India.
October 1985 to April 2007

Visiting Professor, Department of Biomechanics
Ecole Polytechnique Federal de Lausanne (EPFL),
Lausanne, Switzerland, October 1-31, 2006.

Visiting Scientist, Faculty of Pharmacy,
University of Paris-Sud (Paris XI), Chateney-Malabry, France.September-October, 1996; October, 2003; November 2004, November 2005.

JSPS Invitation Fellow, Department of Applied Chemistry,
Toyo University, Saitama, Japan.
November 2003-December 2003.
                       
Visiting Scientist, Dept. of Materials Science & Engineering,
University of Florida, Gainesville, Florida, USA.
May 1990 to June 1991.

British Council Scholar, Institute of Medical and Dental Bioengineering,
University of Liverpool, England.
June 1989 to September 1989.

Pool Officer (CSIR), Dept. of Inorganic and Physical Chemistry,
Indian Institute of Science, Bangalore, India.
April 1984 to September 1985.

Postdoctoral Associate, Biomedical Engineering Center,
Dept. of Materials Science & Engineering,
University of Florida, Gainesville, Florida, USA.
July 1982 to March 1984.
                       
Postdoctoral Associate, Dept. of Chemical Engineering,
University of Florida, Gainesville, Florida, USA.
March 1981 to July 1982.

Postdoctoral Fellow, Department of Chemistry,
Indian Institute of Technology, Madras, India.
August 1980 to March 1981.

Honours/Awards:

Distinguished Alumnus Award of  Indian Institute of Technology Madras for Academic Excellence, 2005.

The Shah-Schulman Award for the best Ph.D thesis in the field of Surface Science for the year 2007 (The highest award for a Ph.D thesis in India in the field of surface science that carries a cash award of Rs. 40,000 and a citation, awarded to Ph.D student Ms. Biji Balakrishnan).
 
Fellow, Indian Academy of Sciences, Bangalore, Elected 2001.

Recipient- Materials Research Society of India (MRSI) Medal for 1997.

Regional Award of  the International Society for Artificial Organs (ISAO), USA for India, Middle East and Africa, 1997 for the paper entitled, “Migration resistant, blood-compatible plasticized poly(vinyl chloride) for medical and related applications”.

Member, UPSC board for selection of civil service officers of IAS, IFS etc., 2005

Member-International Editorial Board of the International Journal Biomaterials, Published by Elsevier Science Ltd, United Kingdom, from 1997.

Session Chair of many National and International Conferences in the area of Biomaterials and Drug Delivery.

Listed in Marquis Who’s Who in the World.

Recipient‑Special Topic Award (Biotechnology for Development) of the State Committee on Science, Technology and Environment of  the Government of Kerala at the 8th Kerala Science Congress, Cochin, January 29, 1996.

Recipient‑The Society of Cosmetic Chemists' Award for the Best Paper Presented in the Annual Meeting of the Society, December 1981, New York.

Recipient-First Rank in the M. Sc. Degree Examination of the University of Calicut, India, 1975.

Recipient-National Merit Scholarship of the Government of India for B.Sc and M.Sc.

  Selected Patents :
1.US Patent, 4,819,617, E.P. Goldberg, A. Jayakrishnan and M. Yalon, 1989.

2.A process for the manufacture of spherical, highly porous beads of polymers of 2-hydroxyethyl methacrylate (PHEMA), A. Jayakrishnan and B.C. Thanoo. Indian Patent 177753, 1990.

3.A process for the preparation of uncrosslinked and crosslinked PMMA microspheres, A.Jayakrishnan and B.C. Thanoo. Indian Patent 179451, 1991.

4.A process for preparation of hydrogel beads from poly(methyl methacrylate), A. Jayakrishnan and B.C. Thanoo,  Indian Patent 182221, 1991.

5.Double umbrella occluder device for cardiovascular applications, K.R. Mandalam and A. Jayakrishnan,  Indian Patent 184338, 1995.

6. Process for preparation of calcium caseinate beads and granules containing any oral drug, A. Jayakrishnan. Indian Patent  181854, 1996.

7. Migration resistant plasticized poly(vinyl chloride), A. Jayakrishnan (Indian Patent Application 709/MAS/95 dated 13.06.1995.

8. A process for grafting poly(ethylene glycol) onto the surface of plasticized poly(vinyl chloride), A. Jayakrishnan and S. Lakshmi . Indian Patent 183743, 1997.

Selected Recent Publications:

1.A photochemical method for immobilization of dextran onto poly(ethylene terephthalate) surfaces, V. T. Bhat, N. R. James,  A. Jayakrishnan, Polymer International 57, 124-132, 2008.

2. On imparting radiopacity to a poly(urethane urea), N. R. James, A. Jayakrishnan, Biomaterials, 28, 3182-3187, 2007.

3. Surface modification of poly(ethylene terephthalate) by plasma polymerization of poly(ethylene glycol), D. Sakthi Kumar, M. Fujioka , K. Asano, A. Shoji, A. Jayakrishnan, Y. Yoshida, J. Mater. Sci., Mater. Med., 18, 1831-1835, 2007.

4. Synthesis and evaluation of ampicillin-conjugated gum arabic microspheres for sustained release, K. K. Nishi, M. Antony, A. Jayakrishnan, J. Pharm. Pharmacol., 59,485-493, 2007.

5. Amphotericin B-gum arabic conjugates: synthesis, toxicity, bioavailability, and activities against leishmania and fungi, K. K. Nishi, M. Antony, P. V. Mohanan, T. V. Anilkumar, P. M. Loiseau, A. Jayakrishnan, Pharm. Res., 24, 971-980, 2007.

6. Self-gelling primaquine-gum arabic conjugate: An injectable controlled delivery system for primaquine, K. K. Nishi, A. Jayakrishnan, Biomacromolecules, 8, 84-90, 2007.

7. Evaluation of the effect of incorporation of dibutyryl cyclic adenosine monophosphate in an in situ forming hydrogel wound dressing based on oxidized alginate and gelatin, B. Balakrishnan, M. Mohanty, A. C. Fernandez, P. V. Mohanan and A. Jayakrishnan Biomaterials, 27, 1355-1361, 2006.

8. Evaluation of an in situ forming hydrogel wound dressing based on oxidized alginate and gelatin, Biji Balakrishnan, M. Mohanty, P. R. Umashankar, A. Jayakrishnan, Biomaterials, 32, 6335-42, 2005. 

9.Oxidized chondroitin sulphate-cross-linked gelatin matrices: A new class of hydrogels, S. Dawlee, A. Sugandhi, Biji Balakrishnan, D. Labarre, A. Jayakrishnan, Biomacromolecules, 6, 2040-2048, 2005.

10 Self-crosslinking biopolymers as injectable, in-situ forming biodegradable scaffolds, Biji Balakrishnan, A. Jayakrishnan, Biomaterials, 26, 3941-3951, 2005.

11. Chemical modification of poly(vinyl chloride) resin with poly(ethylene glycol) for enhanced blood-compatibility, Biji Balakrishnan, D.S. Kumar, Y. Yoshida, A. Jayakrishnan, Biomaterials, 26, 3495-3502, 2005. 

12.Preparation and evaluation of primaquine-conjugated gum arabic microspheres, K. K. Nishi, A. Jayakrishnan, Biomaromolecules, 5, 1489-1495, 2004.

13. Properties and performance of sulphide-substituted plasticized poly(vinyl chloride)as a biomaterial, S. Lakshmi, A. Jayakrishnan,  J. Biomed. Mater. Res., Part B, 65, 204-210, 2003.  

14.Synthesis and polymerization of a new iodine-containing monomer, S. Lakshmi, Nirmala R. James, V. S. Nisha, A. Jayakrishnan, J. Appl. Polym. Sci ., 88, 2580, 2003.

15. Synthesis, surface properties and performance of thiosulphate-substituted plasticized poly(vinyl chloride), S. Lakshmi, A. Jayakrishnan, Biomaterials, 23, 4855, 2002.

16. A Floating-Type Oral Dosage Form for Piroxicam Based on Hollow Polycarbonate Microspheres: In Vitro and In Vivo Evaluation in Rabbits, N. J. Joseph, S. Lakshmi, A. Jayakrishnan,       J. Control. Rel. 79, 71-79, 2002.

17. Progesterone release from glutaraldehyde cross-linked casein microspheres: In vitro studies and in vivo response in rabbits,  M.S. Latha, A. V. Lal, T.V. Kumary, R. Sreekumar, A. Jayakrishnan, Contraception, 61, 333, 2000.

18. Immobile plasticizer in flexible PVC, A. Jayakrishnan, S. Lakshmi, Nature, 396, 638, 1998.

19. Progesterone-loaded chitosan microspheres: A long acting biodegradable controlled delivery system, S. R. Jameela, T. V. Kumary, A. V. Lal, A. Jayakrishnan, J. Control. Rel. 52, 17, 1998.

20. Migration resistant, blood-compatible plasticized poly(vinyl chloride) for medical and related applications, S. Lakshmi, A. Jayakrishnan, Artificial Organs, 22, 222, 1998.


Selected Invited Reviews/Chapters in Books

1.Polymer microspheres for endovascular embolization, A. Jayakrishnan, S. Joseph, A.K. Gupta, A.S. Rao, in Microspheres, Microcapsules and Liposomes Vol 2: Medical and Biotechnology Applications, R. Arshady, Ed., Citus Books, London, 1999, pp. 97-126.

2. Biodegradable polymeric microspheres as drug carriers, A. Jayakrishnan, M.S. Latha, in Controlled and Novel Drug Delivery, N.K. Jain, Ed., CBS Publishers, New Delhi, 1997.

3. Controlled Drug Delivery Using Microspheres, Nanoparticles and Liposomes, A. Jayakrishnan, D. Labarre, Indo-French Centre for Promotion of Advanced Research, New Delhi, 1999.

4.Amphiphilic Functional Microgels, Reza Arshady, Benedetto Corain, Marco Zecca, A Jayakrishnan, Daniel Horák, in Functional Polymer Colloids & Microparticles, Reza Arshady, Alain Guyot, Eds., Citus Books, London, 2002. 

5. Poly(2-hydroxyethyl methacrylate) Hydrogels. Preparation and Properties, Daniel Horak, A. Jayakrishnan, Reza Arshady, Vol. 1,  Chapter 2, PMS Series, R. Arshady, Ed.,  Citus Books, London, 2003.

 

Presentations (Invited Lectures, Recent Years)

1.In situ forming hydrogels as scaffolds for wound dressing, tissue engineering and drug delivery, Plenarary Lecture, International Conference, Biomaterials Asia 2009, Hong Kong, April 06, 2009.

2. Polymeric Prodrugs Based on Gum Arabic, Key Note Lecture, International Symposium of Frontiers in Biomaterials-Based Drug and Gene Delivery, National Cheng Kung University, Tainan, Taiwan, February 27, 2009.

3. Medical Polymers: Challenges Ad Libitum, Invited Lecture PolymCon 09, International conference on  Polymers, Changing Frontiers, National Institute of Techology, Calicut, January 09, 2009.

4. Polymeric Prodrugs, Invited Lecture, APA International Conference on Advances in Polymer Science and Technology, Organized by Asian Polymer Association, New Delhi, January 28, 2008.

5.In situ forming wound dressing, Invited Lecture, Wound Carecon 08, 2nd annual conference of the society of wound care and researchSCTIMST, Trivandrum, , September 27, 2008.

6. Polymeric Prodrugs of Amphotericn B, Invited Lecture, IUMRS-ICAM International Conference, Hotel Asok, Bangalore, October 12, 2007.

7.Polymeric Prodrugs of Amphotericn B, Invited Lecture, National Symposium on Controlled Release, Controlled Release Society, Indian Chapter, CDRI, Lucknow, June 18, 2007.

8. Polymers for Blood Contact: 25 Years and Still Scratching the Surface, Invited Lecture, Society for Polymer Science, Trivandrum Chapater, Mascot Hotel, March 10, 2007.

9.Polymeric Prodrugs of Amphotericn B, Invited Lecture, BITE & RM-2006, Indo-Australian Conference on Biomaterials, Tissue Engineering and Regenerative Medicine, SCTIMST, Trivandrum, January, 10-12, 2007.

10. Polymers for Biomedical applications, Invited Lecture, S.D. College, Alaphuzha, Organized by the Society of Polymer Science for College Students, November 25, 2006.

11.Surface Modification of Polymers for Medical Applications, Invited Lecture, EPFL, Switzerland, October 27, 2006.

12. In situ Forming, Injectable Hydrogels, Invited Lecture, EPFL, Switzerland, October 13, 2006.

13. Self-Crosslinking Biopolymers as Injectable In Situ Forming Scaffolds, Invited Lecture, Polymer 2006, IACS, Kolkotta, Februay 11, 2006.

14. Medical Polymers: Challenges Ad Libitum, Invited Lecture, International Conference On Advanced Design And Development of Materials, Goa, December 15, 2005  

15. Polymeric Microspheres in Medicine and Surgery, Invited Lecture, Indian Pharamceutical Congress 2005, Hyderabad, December 2, 2005.

16. Biomedical Applications of Polymers, Invited Lecture, Malabar Christian College, Calicut, November 30, 2005.

17.Injectable, In Situ Forming Hydrogels, Invited Lecture, National Seminar on Emerging Trends in Chemistry, University of Calicut, November 30, 2005.

18. Medical Polymers: challenges Ad Libitum, Invited Lecture, National Chemical Laboratory, Pune, September 09, 2005.

19. The Rise and Fall of Tissue Engineering, Invited Lecture, DBT Brainstorming Meeting on Bioengineering, SCTIMST, May 20, 2005.

20.Self-crosslinking polymers as injectable in situ forming polymer scaffolds, Invited Lecure,  Faculty of Pharmacy, University of Paris XI, France, November 8, 2004.

21. Self-crosslinking polymers as injectable in situ forming polymer scaffolds, Invited Lecture,  Department of Biomaterials, University of Maastricht, The Netherlands, November 11, 2004.

22.Polymers for Drug Delivery,  Invited Lecture,  National Seminar on Current Trends in Chemistry, Newmans College, Thodupuzha, January 16, 2004.  

23. Polymers in Medicine, Prof. P. P. Krishnan Endowment Lecture in Chemistry at Malabar Christian College, Calicut, on February, 6, 2004.

24.Polymers: From the  Frying Pan to the Clinic, Invited Lecture, Farook College, Calicut, February 13, 2004.

25. Immobile Plasticizer in Flexible PVC, Invited Lecture, Indo-Australian Seminar on Biomaterials and Tissue Engineering, Manipal Academy of Higher Eduation, February 13, 2004.

26.Immobile Plasticizer in Flexible PVC, Invited lecture, Department of Applied Chemistry, Toyo University, Saitama, Japan, November 21, 2003.

27. Therapeutic Possibilities Using Polymer Microspheres, Invited Lecture, 13th Annual Meeting of the Society for Biomaterials and Artificial Organs- India; CGCRI, Calcutta, December 20-21, 2002.

28.Immobile plasticizer in flexible PVC, Invited Lecture, Indian Academy of Sciences, Annual Meeting, Thirupati, November 9, 2001.

29. Seize the Day: Innovate or Perish, Invited Lecture, National Technology Day Celebrations Organized by the State committee on Science, Technology and Environment, Government of Kerala, Trivandrum, May 29, 2001.

30.Seize the Day: Innovate or Perish, Invited Lecture, National Seminar on Challenges of the new IPR regime and need for new stratagies for R&D and management, Materials Reserch Society of India, Trivandrum, April 27, 2001

31.Polymers for Drug Delivery, Invited Lecture, Indian Science Congress, New Delhi, January 6, 2001.

32.Therapeutic and Prophylactic Opportunities Using Polymeric Microspheres, Invited Lecture, Fourth National Conference of the Indian Society of Chemists and Biologists, CDRI, Lucknow, Jan 28-31, 2000.

 

 

Selected Web Pages on Research Highlights

http://www.nature.com/news/1998/981224/full/981224-3.html
http://news.bbc.co.uk/2/hi/science/nature/236252.stm
www.indianexpress.com/res/web/pIe/ie/daily/19981220/35450044.html

 

 

Editorial Boards:

 

Member, International Editorial Board of the International Journal Biomaterials, Published by Elsevier Science Ltd., UK.

Member, International Editorial Board, Microspheres, Microcapsules and Liposomes, Reference Series, Citus Books, London.

Member, International Editorial Board, Polymeric Biomaterials, Reference Series, Citus Books, London.

Member, International Editorial Borard, International Journal of Biomaterials Research and Engineering, IRMA, Singapore.

Member, International Editorial Board, Open Biomaterials Journal, Bentham, USA.

 

 

Referee:

 

Journal of Controlled Release (Elsevier), Biomaterials (Elsevier), Journal of Biomedical Materials Research (Wiley), European Journal of Pharmaceutics (Elsevier), International Journal of Pharamceutics (Elsevier), Biomacromolecules (ACS), Bulletin of Materials Science (Ind. Acad. Sci), Journal of Applied Polymer Science (Wiley), Journal of Biological Macromolecules (Elsevier), Proceedings-Chemical Sciences (Ind. Acad. Sci.), Polymer International (Wiley), Journal of Pharmacy and Pharmacology (British Pharm Asscoc), Pharmaceutical Research (Elsevier)

 

Membership in Committees:

 

1.Member, Senate of IIT Madras (2007-).

2. Member, Local Board of Administration, Sainik School, Kazhakootam, Trivandrum, December 2008-Present.

3. Member, Governing Council, TechnoPark, Trivandrum, December 2008-Present.

4. Member, Academic Council, Rajiv Gandhi Centre for Biotechnology, 2008-Present.

5. Chairman, Jan Shikshan Sansthan, Trivandrum, December 2008-Present.

6. Member, Institute Body, Sree Chitra Tirunal Institute, December 2008-Present..

7. Member, Departmental Consultative Committee, Dept of Biotech., IIT Madras (2007-)

8. Member, SARD Committee, Kerala State Council for Science and Technology (2007-).

9. Member, Sectional Committee on Engg & Tech., Indian Academy of Sciences, (2007-).

10. Member, Academic Committee of  Sree Chitra Tirunal Institute (2002-2007).

11. Memebr, DBT Task Force on Bioengineering (2005-).

12. Member, UPSC Board for selction of civil service officers (2005).

13. Member, Technology Development Committee of SCTIMST, 1992 to 1997.

14. Member‑Secretary, Research Advisory Committee of SCTIMST, 1987‑1990.
 
 

Membership in Professional Bodies:

 

1.Fellow, Indian Academy of Sciences, Bangalore (Elected 2001). 

2. Member, American Chemical Society (Up to 2007)  

3. Life‑Member, Society for Biomaterials & Artificial Organs (India)

4. Life-Member, Society of Polymer Science (India).

5. Life-Member, Materials Research Society of India.

6. Founder Vice President, Asian Polymer Association, 2007
  Travel: USA, UK, France, Switzerland, Australia, The Netherlands, Italy, Hong Kong, Taiwan, Dubai and  Japan.
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